| Autor: |
Tzur YB; Department of Genetics, Harvard Medical School, Boston, Massachusetts 02115., Friedland AE, Nadarajan S, Church GM, Calarco JA, Colaiácovo MP |
| Jazyk: |
angličtina |
| Zdroj: |
Genetics [Genetics] 2013 Nov; Vol. 195 (3), pp. 1181-5. Date of Electronic Publication: 2013 Aug 26. |
| DOI: |
10.1534/genetics.113.156075 |
| Abstrakt: |
We adapted the CRISPR-Cas9 system for template-mediated repair of targeted double-strand breaks via homologous recombination in Caenorhabditis elegans, enabling customized and efficient genome editing. This system can be used to create specific insertions, deletions, and base pair changes in the germline of C. elegans. |
| Databáze: |
MEDLINE |
| Externí odkaz: |
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