| Autor: |
Michael BR; a Department of Pharmacognosy, Faculty of Pharmacy , Mansoura University (MU) , Mansoura , 35516 , Egypt., Gedara SR, Amer MM, Stevenson L, Ahmed AF |
| Jazyk: |
angličtina |
| Zdroj: |
Natural product research [Nat Prod Res] 2013; Vol. 27 (24), pp. 2281-5. Date of Electronic Publication: 2013 Aug 20. |
| DOI: |
10.1080/14786419.2013.825916 |
| Abstrakt: |
A new highly oxygenated pseudoguaianolide, rudbeckolide (1), was isolated from Rudbeckia hirta L. flowers. The structure of this terpenoid lactone was established on the basis of extensive 1D and 2D NMR spectroscopic analyses. The compound exhibited strong 5-lipoxygenase inhibitory activity (84.9% inhibition at 10 μg/mL) in vitro and the result provided partial evidence for the usage of the plant as traditional medicine. |
| Databáze: |
MEDLINE |
| Externí odkaz: |
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