Morning plasma cortisol is low among obese women with polycystic ovary syndrome.

Autor: Shabir I; Department of Endocrinology & Metabolism and., Ganie MA, Praveen EP, Khurana ML, John J, Gupta N, Kumar G, Ammini AC
Jazyk: angličtina
Zdroj: Gynecological endocrinology : the official journal of the International Society of Gynecological Endocrinology [Gynecol Endocrinol] 2013 Dec; Vol. 29 (12), pp. 1045-7. Date of Electronic Publication: 2013 Aug 19.
DOI: 10.3109/09513590.2013.829449
Abstrakt: Polycystic ovary syndrome (PCOS) is the most common cause for androgen excess in women. It is associated with wide variety of metabolic disorders. The present study assessed morning plasma cortisol in women with PCOS. One hundred and ninety seven cases and 55 controls were enrolled for this study. The mean age of patients and controls were 23 ± 5.6 years and 25 ± 4.3 years. One hundred twelve (56%) women with PCOS had BMI >25. Serum cortisol levels were significantly higher in lean PCOS women compared to controls (13.4 ± 5.1 versus 11.3 ± 4.5, p < 0.01) and over-weight PCOS women group (13.4 ± 5.1 versus 9.3 ± 3.2, p < 0.01). There was a trend for less acne and hirsutism with increase in BMI. Morning plasma cortisol was lower among obese women with PCOS. Morning plasma cortisol correlated negatively with BMI in PCOS women with normal glucose tolerance.
Databáze: MEDLINE
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