Scalable graphene field-effect sensors for specific protein detection.

Autor: Saltzgaber G; Department of Physics, Oregon State University, Corvallis, OR 97331, USA., Wojcik P, Sharf T, Leyden MR, Wardini JL, Heist CA, Adenuga AA, Remcho VT, Minot ED
Jazyk: angličtina
Zdroj: Nanotechnology [Nanotechnology] 2013 Sep 06; Vol. 24 (35), pp. 355502. Date of Electronic Publication: 2013 Aug 06.
DOI: 10.1088/0957-4484/24/35/355502
Abstrakt: We demonstrate that micron-scale graphene field-effect transistor biosensors can be fabricated in a scalable fashion from large-area chemical vapor deposition derived graphene. We electrically detect the real-time binding and unbinding of a protein biomarker, thrombin, to and from aptamer-coated graphene surfaces. Our sensors have low background noise and high transconductance, comparable to exfoliated graphene devices. The devices are reusable and have a shelf-life greater than one week.
Databáze: MEDLINE