| Autor: |
Lim SK; Animal, Plant, and Fisheries Quarantine and Inspection Agency, 175 Anyang-ro, Manan-gu, Anyang 430-757, Republic of Korea. imsk0049@korea.kr, Nam HM, Lee HS, Kim AR, Jang GC, Jung SC, Kim TS |
| Jazyk: |
angličtina |
| Zdroj: |
Journal of food protection [J Food Prot] 2013 Aug; Vol. 76 (8), pp. 1443-6. |
| DOI: |
10.4315/0362-028X.JFP-13-069 |
| Abstrakt: |
Apramycin resistance was observed in 22.8% (81 of 355) of Salmonella Typhimurium isolates collected from pigs from 1998 through 2009 in Korea. All apramycin-resistant Salmonella Typhimurium isolates also were cross-resistant to gentamicin and tobramycin. Among the seven types of aminoglycoside resistance genes tested, only four types were detected in the apramycin-resistant Salmonella Typhimurium isolates: aac (3)-IV, aac (3)-II, aac (3)-III, and ant (2'')-I. Although the aac (3)-IV gene was found in all apramycin-resistant Salmonella Typhimurium isolates, aac (3)-II, aac (3)-III, and ant (2'')-I genes were detected in five (6.2%), two (2.5%), and three (3.7%) isolates, respectively. The apramycin-resistant isolates comprised six phage types, of which PT193 (16 of 81 isolates, 19.8%) was most commonly observed. To our knowledge, this is the first report describing characteristics of apramycin-resistant Salmonella Typhimurium isolates in Korea. Further study is warranted to determine whether apramycin use in animals results in cross-resistance to gentamicin, which may affect public health when gentamicin is required for disease treatment in humans. |
| Databáze: |
MEDLINE |
| Externí odkaz: |
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