[An experimental study of the cardio- and hemodynamic effects of the carboxyl ionophore monensin].

Autor: Gurbanov KG, Kovalev GV, Paperno AA
Jazyk: ruština
Zdroj: Farmakologiia i toksikologiia [Farmakol Toksikol] 1990 May-Jun; Vol. 53 (3), pp. 17-9.
Abstrakt: The effect of ionophore monensin on the main parameters of cardio- and hemodynamics was studied in the experiments on anesthetized cats. Monensin (0.075-0.375 mg/kg) administered intravenously in the increasing doses was shown to produce the dose-dependent elevation of arterial blood pressure, the increase of myocardial contractility and the total peripheral resistance. A single administration of monensin (0.375 mg/kg) was found to exert the two-phase action on the parameters of cardio- and hemodynamics.
Databáze: MEDLINE