| Autor: |
Gur'ianov ID, Karamova NS, Iusupova DV, Gnezdilov OI, Koshkarova LA |
| Jazyk: |
ruština |
| Zdroj: |
Bioorganicheskaia khimiia [Bioorg Khim] 2013 Jan-Feb; Vol. 39 (1), pp. 121-8. |
| DOI: |
10.7868/s0132342312060048 |
| Abstrakt: |
The prodigiosin preparation was isolated and purified from Serratia marcescens ATCC 9986, using chromatographic methods. The analysis of the preparation by TLC, NMR-spectrometry and mass-spectrometry allowed to confirm the red pigment fraction as the prodigiosin and detect its purity. Originally, the specific features of the toxic and genotoxic effects of prodigiosin and the possibility of induction of mutations by pigment in the cells of Salmonella typhimurium TA 100 (Ames test) and chromosome damage of mammalian erythroblasts have been determined. |
| Databáze: |
MEDLINE |
| Externí odkaz: |
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