HLA-G 5' URR SNPs and 3' UTR 14-bp insertion/deletion polymorphism in an Afro-Brazilian population from Paraná State.

Autor: Tureck LV; Department of Genetics, Laboratory of Immunogenetics and Histocompatibility, Universidade Federal do Paraná, Curitiba, Brazil., Santos LC, Wowk PF, Mattar SB, Silva JS, Magalhães JC, Roxo VM, Bicalho MG
Jazyk: angličtina
Zdroj: International journal of immunogenetics [Int J Immunogenet] 2014 Feb; Vol. 41 (1), pp. 29-33. Date of Electronic Publication: 2013 Jul 07.
DOI: 10.1111/iji.12068
Abstrakt: The present study investigated 23 SNPs in the 5'URR promoter region and the 14 bp ins/del polymorphism at the 3'UTR region of the HLA-G gene in 150 individuals with Afro-Brazilian ancestry. Three haplotypes were found to be the most frequent. Comparing these polymorphisms in other samples, our data suggest that Afro-Brazilians are more similar to the Euro-Brazilians than to Hutterite population.
(© 2013 John Wiley & Sons Ltd.)
Databáze: MEDLINE
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