[Energy metabolism in the brain during experimental hemorrhagic shock].

Autor: Loginova MP, Assur MV, Boldina IG
Jazyk: ruština
Zdroj: Voprosy meditsinskoi khimii [Vopr Med Khim] 1990 May-Jun; Vol. 36 (3), pp. 20-4.
Abstrakt: State of energy metabolism was studied in brain of rats at agonal steps caused by bleeding during severe and long-term hypotension (30 mmHg, up to 30 hrs). Fast loss of high energy-containing phosphates, cell energy potential of adenine nucleotides and an increase in the lactate/pyruvate ratio were found in non-resistant rats. At the same time, in the most resistant rats normal content of creatine phosphate, ATP was maintained; energy potential was unaltered and anaerobic glycolysis was not activated. Content of glucose and glycogen did not alter considerably in all the animals studied.
Databáze: MEDLINE