Episode of coexisting infections with multiple dengue virus serotypes in central Karnataka, India.
| Autor: | Vinodkumar CS; Department of Microbiology, S. S. Institute Medical Sciences & Research Centre, NH-4, Bypass Rd, Davangere 577005, Karnataka, India. vinodmicro@yahoo.com, Kalapannavar NK, Basavarajappa KG, Sanjay D, Gowli C, Nadig NG, Prasad BS |
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| Jazyk: | angličtina |
| Zdroj: | Journal of infection and public health [J Infect Public Health] 2013 Aug; Vol. 6 (4), pp. 302-6. Date of Electronic Publication: 2013 Apr 03. |
| DOI: | 10.1016/j.jiph.2013.01.004 |
| Abstrakt: | Background: The co-circulation of multiple dengue virus serotypes has been reported in many parts of the world, including India; however, concurrent infection with more than one serotype of dengue virus in the same individual is rarely documented. Method: An outbreak of dengue hemorrhagic fever/dengue shock syndrome (DHF/DSS) occurred in and around Davangere, Karnataka, from June 2011-March 2012. This is the first report from India with a high percentage of concurrent infections with different dengue virus serotypes circulating during one outbreak. Acute phase sera from patients were tested for the presence of dengue virus RNA by RT-PCR. Results: Of the 72 samples tested for dengue virus RNA, 42 (58.3%) were positive. All four dengue virus serotypes were found to be co-circulating in this outbreak, and DENV-2 was the predominant serotype. In addition, concurrent infection with more than one dengue virus serotype was identified in 18 (42.9%) dengue virus-positive samples. Conclusion: Our study showed that serotype DEN-2 was dominant in the positive dengue virus-infected samples; the other serotype present was DEN-3. This is the first report of concurrent infections with different dengue virus serotypes in this part of the world. (Copyright © 2013 King Saud Bin Abdulaziz University for Health Sciences. Published by Elsevier Ltd. All rights reserved.) |
| Databáze: | MEDLINE |
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