[Influence of plant extracts on the activity of cholera toxin of Vibrio cholerae].
| Autor: | Markina OV, Alekseeva LP, Markin NV, Telesmanich NR |
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| Jazyk: | ruština |
| Zdroj: | Zhurnal mikrobiologii, epidemiologii i immunobiologii [Zh Mikrobiol Epidemiol Immunobiol] 2013 Jan-Feb (1), pp. 9-13. |
| Abstrakt: | Aim: Study the activity of plant extracts against cholera toxin (CT) of Vibrio cholerae O1. Materials and Methods: Antitoxic activity of plant extracts was determined by using enzyme immunoassay and CHO-K1 cell culture. Results: 8 water extracts of plants were studied. Extracts of nut, tutsan, milfoil, basil do not have effect on CT activity in EIA or CHO-K1 cell culture. Celandine and rhubarb extracts do not reduce CT immunochemical activity but prevent elongation of CHO-K1 cells. Oak and hop extracts suppress binding in EIA of cholera toxin and GM1 receptors and insignificantly reduce its activity in cell culture. Conclusion: Antitoxic activityofplant extracts against CT is perspective for the development of preparations possessing inhibition effect. |
| Databáze: | MEDLINE |
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