Gold nanoparticles - the theranostic challenge for PPPM: nanocardiology application.

Autor: Spivak MY; Zabolotny Institute of Microbiology and Virology, National Academy of Sciences of Ukraine, Zabolotny Str,, 154, Kyiv 03680, Ukraine. rostbubnov@gmail.com., Bubnov RV, Yemets IM, Lazarenko LM, Tymoshok NO, Ulberg ZR
Jazyk: angličtina
Zdroj: The EPMA journal [EPMA J] 2013 Jun 24; Vol. 4 (1), pp. 18. Date of Electronic Publication: 2013 Jun 24.
DOI: 10.1186/1878-5085-4-18
Abstrakt: The article overviews the potential biomedical applications of nanoscale gold particles for predictive, preventive and personalised nanomedicine in cardiology. The review demonstrates the wide opportunities for gold nanoparticles due to their unique biological properties. The use of gold nanoparticles in cardiology is promising to develop fundamentally new methods of diagnosis and treatment. The nanotheranostics in cardiovascular diseases allows the non-invasive imaging associated with simultaneous therapeutic intervention and predicting treatment outcomes. Imaging may reflect the effectiveness of treatment and has become a fundamental optimisation setting for therapeutic protocol. Combining the application of biomolecular and cellular therapies with nanotechnologies foresees the development of complex integrated nanodevices. Nanocardiology may challenge existing healthcare system and economic benefits as cardiovascular diseases are the leading cause of morbidity and mortality at present.
Databáze: MEDLINE