| Autor: |
Brecher SM; Pathology and Laboratory Medicine, VA Boston Healthcare System, West Roxbury., Novak-Weekley SM, Nagy E |
| Jazyk: |
angličtina |
| Zdroj: |
Clinical infectious diseases : an official publication of the Infectious Diseases Society of America [Clin Infect Dis] 2013 Oct; Vol. 57 (8), pp. 1175-81. Date of Electronic Publication: 2013 Jun 20. |
| DOI: |
10.1093/cid/cit424 |
| Abstrakt: |
Single molecular or multistep assays (glutamate dehydrogenase, toxin A/B, ± molecular) are recommended for the diagnosis of CDI in patients with clinically significant diarrhea. Rapid and accurate tests can improve resource allocations and improve patient care. Enzyme immunoassay (EIA) for toxins A/B is too insensitive for use as a stand-alone assay. This guideline will examine the use of molecular tests and multitest algorithms for the diagnosis of Clostridium difficile infection (CDI). These new tests, alone or in a multistep algorithm consisting of >1 assay, are more expensive than the older EIA assays; however, rapid and accurate testing can save money overall by initiating appropriate treatment and infection control protocols sooner and by possibly reducing length of hospital stay. We recommend testing only unformed stool in patients with clinically significant diarrhea by a molecular method or by a 2- to 3-step algorithm. |
| Databáze: |
MEDLINE |
| Externí odkaz: |
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