Autologous fat grafting: current state of the art and critical review.
| Autor: | Ross RJ; From the *Taylor Laboratory, Department of Anatomy and Neurosciences, University of Melbourne; †Department of Plastic and Reconstructive Surgery, Royal Melbourne Hospital and University of Melbourne, Parkville; and ‡Australian Catholic University, Victoria Pde, Fitzroy, Victoria, Australia., Shayan R, Mutimer KL, Ashton MW |
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| Jazyk: | angličtina |
| Zdroj: | Annals of plastic surgery [Ann Plast Surg] 2014 Sep; Vol. 73 (3), pp. 352-7. |
| DOI: | 10.1097/SAP.0b013e31827aeb51 |
| Abstrakt: | Background: Despite the widespread use of autologous fat grafting in both reconstructive and cosmetic surgery, volume retention remains a significant problem. We aimed to critically appraise the current body of literature in fat grafting to provide a framework to guide application and comparison. Method: Search of scientific databases and gray literature was conducted. Articles examining nonadipogenic applications of adipose tissue and those specific to breast reconstruction were excluded. Results: One hundred three articles were included. These fell under the headings of donor site, effect of infiltration solution, harvest method, effect of centrifugation, reinjection method, supplementation, the role of adipose-derived stem cells, and scaffolding. Conclusions: Despite the significant research effort in this field, there remains no consensus as to the optimum technique. This stems from the vast array of research methods and short follow-up durations. Further, extrapolation of in vitro results to clinical settings has led to many conflicting practices. |
| Databáze: | MEDLINE |
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