[Experimental models of lysosomal phase reactivity in blood leukocytes exposed to low doses of potassium cyanide].

Autor: Dolgushin MV, Khomuev GD
Jazyk: ruština
Zdroj: Meditsina truda i promyshlennaia ekologiia [Med Tr Prom Ekol] 2013 (3), pp. 36-40.
Abstrakt: Cytochemical analysis of acid phosphatase was used to evaluate lysosomal membranes stability under oral intake of potassium cyanide by rats over one month in daily doses of 1.30 mg/kg (1/10 LD50) and 0.65 mg/kg (1/20 LD50). The authors demonstrated phase-related dose-dependent changes in the lysosomal state, and the main response feature was associated with functional activation that usually followed the membrane alteration.
Databáze: MEDLINE