[Experimental models of lysosomal phase reactivity in blood leukocytes exposed to low doses of potassium cyanide].
Autor: | Dolgushin MV, Khomuev GD |
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Jazyk: | ruština |
Zdroj: | Meditsina truda i promyshlennaia ekologiia [Med Tr Prom Ekol] 2013 (3), pp. 36-40. |
Abstrakt: | Cytochemical analysis of acid phosphatase was used to evaluate lysosomal membranes stability under oral intake of potassium cyanide by rats over one month in daily doses of 1.30 mg/kg (1/10 LD50) and 0.65 mg/kg (1/20 LD50). The authors demonstrated phase-related dose-dependent changes in the lysosomal state, and the main response feature was associated with functional activation that usually followed the membrane alteration. |
Databáze: | MEDLINE |
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