In vitro effect of calcium nanophosphate and high-concentrated fluoride agents on enamel erosion: an AFM study.

Autor: Medeiros IC; Department of Dentistry, Federal University of Campina Grande, UFCG, Patos, PB, Brazil., Brasil VL, Carlo HL, Santos RL, De Lima BA, De Carvalho FG
Jazyk: angličtina
Zdroj: International journal of paediatric dentistry [Int J Paediatr Dent] 2014 May; Vol. 24 (3), pp. 168-74. Date of Electronic Publication: 2013 Jun 19.
DOI: 10.1111/ipd.12046
Abstrakt: Background: Calcium nanophosphate paste can provide ions to remineralize enamel. There are, however, no data available about the remineralizing effect of this paste on the prevention of enamel erosion, when compared with highly concentrated fluoride agents.
Aim: To analyze the effect of calcium nanophosphate paste, fluoride gel, and varnish to protect against enamel erosion using surface Knoop hardness (KNH) and atomic force microscopy (AFM).
Design: Forty enamel blocks (4 × 4 mm) of third molars were used for 4 groups (n = 10): 1.23% fluoride gel (Fluorgel-DFL(®) ); calcium nanophosphate paste (Desensibilize NanoP-FGM(®) ); fluoride varnish (Duraphat-Colgate(®) ) and control (without agent). The specimens were immersed in cola drink for 5 min and 2 h in artificial saliva, 4× per day for 5 days. The agents were applied before the first erosive cycle. KNH values were obtained before and after the erosive challenge. The surface morphology was evaluated by AFM. anova, Tukey's, and T-Student tests were applied.
Results: After erosion, no significant difference was found for KNH among gel, nanophosphate, and varnish groups; however, they showed higher KNH than control group. Gel and nanophosphate paste showed a protective layer formation on enamel surface by AFM.
Conclusions: The calcium nanophosphate paste showed similar protection against enamel erosion compared with high-concentrated fluoride agents, even containing lower fluoride concentration.
(© 2013 BSPD, IAPD and John Wiley & Sons A/S. Published by John Wiley & Sons Ltd.)
Databáze: MEDLINE
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