| Autor: |
Manvelian ÉA, Baturin VA, Anisimova NA |
| Jazyk: |
ruština |
| Zdroj: |
Eksperimental'naia i klinicheskaia farmakologiia [Eksp Klin Farmakol] 2013; Vol. 76 (4), pp. 7-10. |
| Abstrakt: |
It is established that adrenalectomy decreases the "sedative" and "anti-anxiety" effects and reduces the "anxiogenic" effect of diazepam in male rats under multiparametric test conditions. At the same time, the "sedative" and "activating" effects of this tranquilizer do not appear in adrenalectomized female rats and the "anti-anxiety" effect is only observed in the evening. The "anxiogenic" effect of diazepam in females is not observed for a drug dose of 0.5 mg/kg and is only manifested at a dose of 0.1 mg/kg. |
| Databáze: |
MEDLINE |
| Externí odkaz: |
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