Neuroendocrine tumor in the liver of a patient with isolated polycystic liver disease: A case report and review of the literature.

Autor: Koutsampasopoulos K; Department of Internal Medicine, General Hospital of Naoussa, Thessaloniki, Greece., Antoniadou E, Zoutis S, Iacovidis G, Burova O, Taplidis A
Jazyk: angličtina
Zdroj: Oncology letters [Oncol Lett] 2013 May; Vol. 5 (5), pp. 1664-1666. Date of Electronic Publication: 2013 Mar 06.
DOI: 10.3892/ol.2013.1233
Abstrakt: Neuroendocrine tumors (NETs) frequently metastasize to the liver, but it is rare to find them there as primary tumors. Isolated polycystic liver disease (PCLD) is a rare autosomal dominant disease. There is no known association between polycystic liver disease and neuroendocrine or other tumors. We report a case of a 64-year-old female with a past medical history of isolated PCLD who presented with increasing abdominal pain over a two-week period. Our patient underwent open surgical biopsy one month after presentation. The histological examination and immunohistochemical findings suggested an intermediate grade neuroendocrine tumor. A 24-h delayed whole-body scintigraphy technique was utilized for the identification and localization of neuroendocrine tumors via the administration of In-111-labeled OctreoScan; however, no extrahepatic accumulation was observed. No previous studies in the literature describe a patient with PCLD and a primary or metastatic neuroendocrine tumor of the liver.
Databáze: MEDLINE