| Autor: |
Hidalgo L; Department of Animal Health and VISAVET, Universidad Complutense de Madrid, Madrid, Spain., Gutierrez B, Ovejero CM, Carrilero L, Matrat S, Saba CK, Santos-Lopez A, Thomas-Lopez D, Hoefer A, Suarez M, Santurde G, Martin-Espada C, Gonzalez-Zorn B |
| Jazyk: |
angličtina |
| Zdroj: |
Antimicrobial agents and chemotherapy [Antimicrob Agents Chemother] 2013 Sep; Vol. 57 (9), pp. 4532-4. Date of Electronic Publication: 2013 Jun 10. |
| DOI: |
10.1128/AAC.00491-13 |
| Abstrakt: |
Seven Klebsiella pneumoniae isolates from dogs and cats in Spain were found to be highly resistant to aminoglycosides, and ArmA methyltransferase was responsible for this phenotype. All isolates were typed by multilocus sequence typing (MLST) as ST11, a human epidemic clone reported worldwide and associated with, among others, OXA-48 and NDM carbapenemases. In the seven strains, armA was borne by an IncR plasmid, pB1025, of 50 kb. The isolates were found to coproduce DHA-1 and SHV-11 β-lactamases, as well as the QnrB4 resistance determinant. This first report of the ArmA methyltransferase in pets illustrates their importance as a reservoir for human multidrug-resistant K. pneumoniae. |
| Databáze: |
MEDLINE |
| Externí odkaz: |
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