Long-term health experience of jet engine manufacturing workers: VIII. glioblastoma incidence in relation to workplace experiences with parts and processes.
| Autor: | Marsh GM; Center for Occupational Biostatistics and Epidemiology, Department of Biostatistics, Graduate School of Public Health, University of Pittsburgh, Pittsburgh, PA 15261, USA. gmarsh@pitt.edu, Youk AO, Buchanich JM, Downing S, Kennedy KJ, Esmen NA, Hancock RP, Lacey SE, Pierce JS, Fleissner ML |
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| Jazyk: | angličtina |
| Zdroj: | Journal of occupational and environmental medicine [J Occup Environ Med] 2013 Jun; Vol. 55 (6), pp. 690-708. |
| DOI: | 10.1097/JOM.0b013e3182871583 |
| Abstrakt: | Objective: To determine whether glioblastoma (GB) incidence rates among jet engine manufacturing workers were associated with workplace experiences with specific parts produced and processes performed. Methods: Subjects were 210,784 workers employed between 1952 and 2001. We conducted nested case-control and cohort incidence studies with focus on 277 GB cases. We estimated time experienced with 16 part families, 4 process categories, and 32 concurrent part-process combinations with 20 or more GB cases. Results: In both the cohort and case-control studies, none of the part families, process categories, or both considered was associated with increased GB risk. Conclusions: If not due to chance alone, the not statistically significantly elevated GB rates in the North Haven plant may reflect external occupational factors or nonoccupational factors unmeasured in the current evaluation. |
| Databáze: | MEDLINE |
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