| Autor: |
Avlonitis N; EaStChem, School of Chemistry, University of Edinburgh, West Mains Road, EH9 3JJ, Edinburgh, UK., Debunne M, Aslam T, McDonald N, Haslett C, Dhaliwal K, Bradley M |
| Jazyk: |
angličtina |
| Zdroj: |
Organic & biomolecular chemistry [Org Biomol Chem] 2013 Jul 14; Vol. 11 (26), pp. 4414-8. Date of Electronic Publication: 2013 May 28. |
| DOI: |
10.1039/c3ob40212f |
| Abstrakt: |
Human neutrophil elastase (HNE) is a serine protease implicated in the pathogenesis of acute and chronic inflammatory disease. Here a series of, internally quenched, single fluorophore fluorescent reporters were synthesised that allowed the rapid, highly specific and sensitive analysis of HNE activity over closely related proteases. |
| Databáze: |
MEDLINE |
| Externí odkaz: |
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