| Autor: |
Kuz'mitskiĭ BB, Dad'kov IG, Mashkovich AE, Stoma OV, Slepneva LM |
| Jazyk: |
ruština |
| Zdroj: |
Farmakologiia i toksikologiia [Farmakol Toksikol] 1990 Mar-Apr; Vol. 53 (2), pp. 52-5. |
| Abstrakt: |
Two structural analogues of D-homo-8-azasteroids, both an immunostimulant and an immunodepressant, are inductors of the liver cytochrome P-450 in animals. This capability was shown by means of both a decrease of the hexenal sleep duration in the pharmacological test and an increase of the quantity of cytochrome P-450 and the rate of N-demethylation of aminopyrine in the biochemical assays. |
| Databáze: |
MEDLINE |
| Externí odkaz: |
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