Large-cell neuroendocrine carcinoma of prostate. Case report.

Autor:	Moratalla Charcos LM; Service of Urology, Hospital Universitario Dr. Peset, Valencia, Spain. luzmoratalla@comv.es, Pastor Navarro T, Cortes Vizcaino V, Osca Garcia JM, Gil Salom M
Jazyk:	English; Spanish; Castilian
Zdroj:	Archivos espanoles de urologia [Arch Esp Urol] 2013 May; Vol. 66 (4), pp. 368-71.
Abstrakt:	Objective: To report a case of a neuroendocrine differentiation in a prostate cancer patient, a rare subtype. Methods: We describe the case of a patient diagnosed with adenocarcinoma of the prostate initially, who presented hematuria due to disease progression with neuroendocrine differentiation despite androgen-deprivation therapy (ADT ). Discussion: Prostate cancer is the most common tumor in men. Histologically they are diagnosed as adenocarcinomas, which followed by ADT for a long time, develop neuroendocrine differentiation (NED ). Conclusions: The prognostic significance of NED remains controversial. We must think in neuroendocrine differentiation in ADT-treated patient with disease progression and low PSA.
Databáze:	MEDLINE
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