| Autor: |
Artac M; Department of Medical Oncology, Meram Medical Faculty, Necmettin Erbakan University, Konya, Turkey., Koral L, Toy H, Guler T, Boruban MC, Altundag K |
| Jazyk: |
angličtina |
| Zdroj: |
Journal of oncology pharmacy practice : official publication of the International Society of Oncology Pharmacy Practitioners [J Oncol Pharm Pract] 2014 Apr; Vol. 20 (2), pp. 141-5. Date of Electronic Publication: 2013 May 14. |
| DOI: |
10.1177/1078155213480201 |
| Abstrakt: |
Presentation with bone marrow metastasis at diagnosis is a rare event in breast carcinoma. Here, we report a rare presentation of metastatic breast cancer patient with bone marrow metastases, who was successfully treated with trastuzumab combined chemotherapy. The regimens initially applied for bone marrow metastasis were docetaxel/adriamycin, gemcitabine/vinorelbine, epirubicin/cyclophosphamide, capecitabine, docetaxel, gemcitabine, and paclitaxel. But, the best response to these regimens was not satisfactory. Our patient was completely treated with etoposide-cisplatin and trastuzumab combination. She is still on remission after five years of metastatic breast cancer diagnosis using letrozole and trastuzumab without complication. Physicians should be careful in treating bone marrow metastases in breast cancer, since patients can show improved marrow function after chemotherapy and long-lasting survival is possible. |
| Databáze: |
MEDLINE |
| Externí odkaz: |
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