Bacterial isolates from cerebrospinal fluid of children with suspected acute meningitis in a Nigerian tertiary hospital.

Autor:	Nwadioha SI; Department of Medical Microbiology, College of Health Sciences Benue State University, Makurdi.Nigeria., Nwokedi EO, Onwuezube I, Egesie JO, Kashibu E
Jazyk:	angličtina
Zdroj:	The Nigerian postgraduate medical journal [Niger Postgrad Med J] 2013 Mar; Vol. 20 (1), pp. 9-13.
Abstrakt:	Aims and Objectives: To determine the common aetiolog of acute bacterial meningitis in children and their antibiotic susceptibility pattern. Materials and Methods: A retrospective study with a review of cerebrospinal fluid culture reports of paediatric patients aged 0-15 years, suspected of acute meningitis in the Medical Microbiology Department of Aminu Kano Teaching Hospital, Kano, Nigeria from October 2006 to October 2009 from October 2006 to October 2009. Results: A positive culture bacterial isolation rate of 3.3% (n=50/1500) with prevalence of Streptococcus pneumoniae (24%), Neisseria meningitidis (22%), Escherichia coli (16%), Haemophilus influenzae (14%), Group B streptococci (8%) and Enterococci (8%) which were susceptible to ceftriaxone (96%), cefotaxime (95%) and ciprofloxacin (93%) across the bacterial isolates. Neonates were 55% (n=6.8/12.4) most at risk. Conclusion: Neonates are the most at risk of acute bacterial meningitis. In the absence of antibiotic susceptibility report, ceftriaxone should be considered as a first choice reliable antibiotic for empirical treatment of meningitis in children, in this environment.
Databáze:	MEDLINE
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