Autor: |
Goldacre MJ; Unit of Health-Care Epidemiology, Department of Public Health, University of Oxford, Old Road Campus, Oxford, UK., Wotton CJ; Unit of Health-Care Epidemiology, Department of Public Health, University of Oxford, Old Road Campus, Oxford, UK., Maisonneuve JJ; Unit of Health-Care Epidemiology, Department of Public Health, University of Oxford, Old Road Campus, Oxford, UK. |
Jazyk: |
angličtina |
Zdroj: |
Epidemiology and infection [Epidemiol Infect] 2014 Feb; Vol. 142 (2), pp. 371-8. Date of Electronic Publication: 2013 May 10. |
DOI: |
10.1017/S095026881300099X |
Abstrakt: |
We used a database of 248 659 births, with follow-up to subsequent disease, in the Oxford record linkage archive (1979-1999) to study the influence of family, maternal, and perinatal factors on subsequent hospital admission for meningococcal, Haemophilus, and enteroviral meningitis in the children. In this summary, we report key findings that were significant in multivariate analysis. Meningococcal meningitis was significantly associated with maternal smoking [odds ratio (OR) 2·1, 95% confidence interval (CI) 1·2-3·7]. Haemophilus meningitis was associated with having older siblings (e.g. second child compared to first-born, OR 3·3, 95% CI 2·0-5·6). Enteroviral meningitis was associated with low birth weight (OR 2·2, 95% CI 1·3-3·6) and male sex (OR 1·7, 95% CI 1·2-2·3). The mothers of six of the 312 children with enteroviral meningitis had previously had enteroviral meningitis themselves. We concluded that several maternal characteristics influence the risk of these types of meningitis. |
Databáze: |
MEDLINE |
Externí odkaz: |
|