| Autor: |
Kondrashova MN, Zakharchenko MV, Khunderiakova NV, Fedotcheva NI, Litvinova EG, Romanova OI, Guliaev AA |
| Jazyk: |
ruština |
| Zdroj: |
Biofizika [Biofizika] 2013 Jan-Feb; Vol. 58 (1), pp. 106-16. |
| Abstrakt: |
Through the use of the original cytobiochemical method to study oxidation in mitochondria, preserving their native organization in network within cells in a blood smear, we revealed hyperactive state of succinate dehydrogenase, which is realized in the organism under physiological stress. It is consistent with the view of the non-equilibrium state of enzymes during activity. The mechanism of the succinate dehydrogenase hyperactivity moderation is based on the full functioning of alpha-ketoglutarate dehydrogenase, supported by oxidation of isocitric acid. |
| Databáze: |
MEDLINE |
| Externí odkaz: |
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