Infiltrating gastric adenocarcinoma with disseminated osteoblastic metastases.

Autor: Santos VM; Armed Forces Hospital, Cruzeiro Novo, Brasilia, Brasil. vitorinomodestos@gmail.com, Vieira TA, Marinho CS, Loures TP, Brandao BB, Botan RN
Jazyk: angličtina
Zdroj: Anales del sistema sanitario de Navarra [An Sist Sanit Navar] 2013 Jan-Apr; Vol. 36 (1), pp. 153-7.
DOI: 10.4321/s1137-66272013000100022
Abstrakt: We report the case of a man with a diagnosis of invasive gastric adenocarcinoma associated with scattered osteoblastic metastases. This 65-year-old patient was admitted with nausea, vomiting and abdominal pain, in addition to loss of weight (13 Kg in 3 months). Upper digestive endoscopy revealed extensive infiltrating changes in the body of the stomach, and histopathologic data confirmed the diagnosis of a Borrmann IV gastric adenocarcinoma. Complementary exams were indicative of a gastric cancer with bone metastases, characterized by disseminated osteoblastic images of the scintigraphy of the skeleton. Palliative chemotherapy was the treatment of first choice. High serum levels of CA 19-9, CEA and alkaline phosphatase can constitute useful indicative tools of this challenging condition. Images from a scintigraphy study of the skeleton can characterize the type and extension of bone metastases. The aim of this case study is to report a case of a very uncommon condition, considering that disseminated osteoblastic metastases rarely develop in this kind of tumor.
Databáze: MEDLINE