Gamma Probe Guided Minimally Invasive Parathyroidectomy without Quick Parathyroid Hormone Measurement in the Cases of Solitary Parathyroid Adenomas.
| Autor: | Karyağar S; Trabzon Kanuni Training and Research Hospital, Department of Nuclear Medicine, Trabzon, Turkey., Karyağar SS, Yalçın O, Yüney E, Mülazımoğlu M, Ozpaçacı T, Karatepe O, Ozdenkaya Y |
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| Jazyk: | angličtina |
| Zdroj: | Molecular imaging and radionuclide therapy [Mol Imaging Radionucl Ther] 2013 Apr; Vol. 22 (1), pp. 3-7. Date of Electronic Publication: 2013 Apr 05. |
| DOI: | 10.4274/Mirt.69885 |
| Abstrakt: | Objective: In this study, our aim was to study the efficiency of gamma probe guided minimally invasive parathyroidectomy (GP-MIP), conducted without the intra-operative quick parathyroid hormone (QPTH) measurement in the cases of solitary parathyroid adenomas (SPA) detected with USG and dual phase 99mTc-MIBI parathyroid scintigraphy (PS) in the preoperative period. Material and Methods: This clinical study was performed in 31 SPA patients (27 female, 4 male; mean age 51±11years) between February 2006 and January 2009. All patients were operated within 30 days after the detection of the SPA with dual phase 99mTc-MIBI PS and USG. The GP-MIP was done 90-120 min after the iv injection of 740 MBq 99mTc-MIBI. In all cases, except 1 patient, the GP-MIP was performed under local anesthesia; due to the enormity of size of SPA, then general anesthesia is chosen. Results: The operation time was 30-60 min, mean 38,2±7 min. In the first postoperative day, there was a more than 50% decrease in PTH levels in all patients and all but one had normal serum calcium levels. Transient hypocalcemia was detected in one patient. Conclusion: GP-MIP without intra-operative QPTH measurement is a suitable method in the surgical treatment of SPA detected by dual phase 99mTc-MIBI PS and USG. Conflict of Interest: None declared. |
| Databáze: | MEDLINE |
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