Evaluation of methicillin-resistant Staphylococcus aureus nasal carriage in Malagasy patients.
| Autor: | Rasamiravaka T; Faculty of Medicine, University of Antananarivo, Antananarivo, Madagascar. travaka@yahoo.fr, Rasoanandrasana S, Zafindraibe NJ, Rakoto Alson AO, Rasamindrakotroka A |
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| Jazyk: | angličtina |
| Zdroj: | Journal of infection in developing countries [J Infect Dev Ctries] 2013 Apr 17; Vol. 7 (4), pp. 318-22. Date of Electronic Publication: 2013 Apr 17. |
| DOI: | 10.3855/jidc.2460 |
| Abstrakt: | Introduction: Methicillin-resistant Staphylococcus aureus (MRSA) is an important cause of infections. It is well recognized that nasal carriage of S. aureus represents a potent and increasingly prevalent risk factor for subsequent S. aureus infection. However, in Madagascar no data exist concerning this nasal carriage of S. aureus. Methodology: Nasal swabs from 304 different patients attending the Laboratory of Training and Research in Medical Biology of Madagascar were cultured for methicillin sensitive (MSSA) and MRSA. Results: One hundred and sixteen patients had S. aureus in their noses (38.16 ± 5.46%) of whom 45 (14.80 ± 3.99%) had MRSA. A risk factor for MSSA nasal carriage included a history of hospitalization when antibiotics were administered (odds ratio [OR] 2.25, 1.09 - 4.64). Among MRSA nasal isolates, high rate of resistance to other antibiotics was observed, particularly for trimethoprim-sulfamethoxazole (68.89%), erythromycin (66.67%) and ofloxacin (53.33%). Conclusions: Our data showed a high rate of MRSA nasal carriage and a high rate of multidrug resistance. A strategic policy against the spread of multidrug resistant strains is desirable. |
| Databáze: | MEDLINE |
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