| Autor: |
Madan K; Institute of Human Genetics, Free University, Amsterdam, The Netherlands., Pieters MH, Kuyt LP, van Asperen CJ, de Pater JM, Hamers AJ, Gerssen-Schoorl KB, Hustinx TW, Breed AS, Van Hemel JO, et. al. |
| Jazyk: |
angličtina |
| Zdroj: |
Human genetics [Hum Genet] 1990 Jun; Vol. 85 (1), pp. 15-20. |
| DOI: |
10.1007/BF00276319 |
| Abstrakt: |
We report the result of investigations from 20 families with 72 carriers of the paracentric inversion inv(11)(q21q23) in the Netherlands. There is no increase in the rate of spontaneous abortions among carriers of the inversion or their partners. Also, so far, there are no children with recombinant chromosomes arising from the inversion. It is doubtful whether prenatal diagnosis would be helpful to carriers of this inversion. The results of the genealogy study and geographical distribution are discussed; it is suggested that all the families have arisen from a single mutation. |
| Databáze: |
MEDLINE |
| Externí odkaz: |
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