Two episodes of anaphylaxis following exposure to hydroxypropyl methylcellulose during cataract surgery.

Autor: Munk SJ; Eye Pathology Institute, Department of Neuroscience and Pharmacology, University of Copenhagen, Copenhagen, Denmark., Heegaard S, Mosbech H, Garvey LH
Jazyk: angličtina
Zdroj: Journal of cataract and refractive surgery [J Cataract Refract Surg] 2013 Jun; Vol. 39 (6), pp. 948-51. Date of Electronic Publication: 2013 Apr 06.
DOI: 10.1016/j.jcrs.2013.02.034
Abstrakt: Unlabelled: We report a case of immediate severe anaphylaxis to hydroxypropyl methylcellulose (HPMC) on 2 separate occasions during cataract surgery in a 71-year-old patient. Skin prick tests were positive for HPMC, a constituent of Ocucoat and Xylocaine gel, which were administered intraocularly during surgery. Skin prick tests were also positive for methylcellulose. Based on symptoms and clinical signs of anaphylaxis following 2 separate cataract operations together with positive prick tests to HPMC, HPMC is the most plausible cause of the reactions. The patient has since had uneventful surgery for a detached retina avoiding HPMC. This case stresses the importance of considering all medication given to patients as possible causes of an anaphylactic reaction.
Financial Disclosure: No author has a financial or proprietary interest in any material or method mentioned.
(Copyright © 2013 ASCRS and ESCRS. Published by Elsevier Inc. All rights reserved.)
Databáze: MEDLINE