Two episodes of anaphylaxis following exposure to hydroxypropyl methylcellulose during cataract surgery.
Autor: | Munk SJ; Eye Pathology Institute, Department of Neuroscience and Pharmacology, University of Copenhagen, Copenhagen, Denmark., Heegaard S, Mosbech H, Garvey LH |
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Jazyk: | angličtina |
Zdroj: | Journal of cataract and refractive surgery [J Cataract Refract Surg] 2013 Jun; Vol. 39 (6), pp. 948-51. Date of Electronic Publication: 2013 Apr 06. |
DOI: | 10.1016/j.jcrs.2013.02.034 |
Abstrakt: | Unlabelled: We report a case of immediate severe anaphylaxis to hydroxypropyl methylcellulose (HPMC) on 2 separate occasions during cataract surgery in a 71-year-old patient. Skin prick tests were positive for HPMC, a constituent of Ocucoat and Xylocaine gel, which were administered intraocularly during surgery. Skin prick tests were also positive for methylcellulose. Based on symptoms and clinical signs of anaphylaxis following 2 separate cataract operations together with positive prick tests to HPMC, HPMC is the most plausible cause of the reactions. The patient has since had uneventful surgery for a detached retina avoiding HPMC. This case stresses the importance of considering all medication given to patients as possible causes of an anaphylactic reaction. Financial Disclosure: No author has a financial or proprietary interest in any material or method mentioned. (Copyright © 2013 ASCRS and ESCRS. Published by Elsevier Inc. All rights reserved.) |
Databáze: | MEDLINE |
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