| Autor: |
Moure AL; Departamento de Química Orgánica, Facultad de Ciencias, Universidad Autónoma de Madrid (UAM), Cantoblanco, 28049 Madrid, Spain., Mauleón P, Gómez Arrayás R, Carretero JC |
| Jazyk: |
angličtina |
| Zdroj: |
Organic letters [Org Lett] 2013 Apr 19; Vol. 15 (8), pp. 2054-7. Date of Electronic Publication: 2013 Apr 09. |
| DOI: |
10.1021/ol4007663 |
| Abstrakt: |
In accessing trisubstituted vinyl boronates from terminal alkynes, a propargyl directing (2-pyridyl)sulfonyl group allows terminal alkynes to undergo Cu-catalyzed B2(pin)2-borylation and subsequent Cu-catalyzed allylic alkylation with Grignard reagents without affecting the pinacolboronate moiety, thereby formally enabling a highly stereo- and regiocontrolled access to hydroboration products of unbiased dialkyl internal alkynes. |
| Databáze: |
MEDLINE |
| Externí odkaz: |
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