Miniprobe endoscopic ultrasonography has limitations in determining the T stage in early colorectal cancer.
Autor: | Tsung PC; Department of Internal Medicine, Inje University Seoul Paik Hospital, Inje University College of Medicine, Seoul, Korea., Park JH, Kim YS, Kim SY, Park WW, Kim HT, Kim JN, Kang YK, Moon JS |
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Jazyk: | angličtina |
Zdroj: | Gut and liver [Gut Liver] 2013 Mar; Vol. 7 (2), pp. 163-8. Date of Electronic Publication: 2013 Feb 07. |
DOI: | 10.5009/gnl.2013.7.2.163 |
Abstrakt: | Background/aims: Mini-probe endoscopic ultrasonography (mEUS) is a useful diagnostic tool for accurate assessment of tumor invasion. The aim of this study was to estimate the accuracy of mEUS in patients with early colorectal cancer (ECC). Methods: Ninety lesions of ECC underwent mEUS for pre-treatment staging. We divided the lesions into either the mucosal group or the submucosal group according to the mEUS findings. The histological results of the specimens were compared with the mEUS findings. Results: The overall accuracy for assessing the depth of tumor invasion (T stage) was 84.4% (76/90). The accuracy of mEUS was significantly lower for submucosal lesions compared to mucosal lesions (p=0.003) and it was lower for large tumors (≥2 cm) (p=0.034). The odds ratios of large tumors and submucosal tumors affecting the accuracy of T staging were 3.46 (95% confidence interval [CI], 1.05 to 11.39) and 6.25 (95% CI, 1.85 to 25.14), respectively. When submucosal tumors were combined with large size, the odds ratio was 14.67 (95% CI, 1.46 to 146.96). Conclusions: The overall accuracy of T stage determination with mEUS was considerably high in patients with ECC; however, the accuracy decreased when tumor size was >2 cm or the tumor had invaded the submucosal layer. |
Databáze: | MEDLINE |
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