| Autor: |
Miniyar PB; Department of Pharm. Chem. Sinhgad Institute of Pharmacy, Narhe, Pune- 411041, India. pankajmpharm@yahoo.co.in, Murumkar PR, Patil PS, Barmade MA, Bothara KG |
| Jazyk: |
angličtina |
| Zdroj: |
Mini reviews in medicinal chemistry [Mini Rev Med Chem] 2013 Oct; Vol. 13 (11), pp. 1607-25. |
| DOI: |
10.2174/1389557511313110007 |
| Abstrakt: |
Pyrazine is one of the important class of heterocyclic compounds that can be obtained naturally or synthesized chemically. Pyrazine ring has got importance in exhibiting various biological activities in association with other scaffolds like pyrrole, pyrazole, imidazole, triazole, tetrazole, thiophene, oxazole, pyridine, piperidine and piperazine. Presence of pyrazine ring as a basic scaffold in various clinically used drugs exhibits its importance in drug design. In this review, attempt has been made to disclose various therapeutic applications of pyrazine derivatives reported during the last decade. |
| Databáze: |
MEDLINE |
| Externí odkaz: |
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