| Autor: |
Sokolova EA, Malkova NA, Korobko DS, Rozhdestvenskiĭ AS, Kakulia AV, Khanokh EV, Delov RA, Platonov FA, Popova TE, Aref'eva EG, Zagorskaia NN, Alifirova VM, Titova MA, Smagina IV, El'chaninova SA, Popovtseva AV, Lichenko IuN, Dymova MA, Vaĭner AS, P'iankova OV, Oskorbin IP, Kechin AA, Puzyrev VP, Kulakova OG, Tsareva EIu, Favorova OO, Shur SG, Lashch NIu, Popova NF, Gusev EI, Boĭko AN, Aul'chenko IuS, Filipenko ML |
| Jazyk: |
ruština |
| Zdroj: |
Zhurnal nevrologii i psikhiatrii imeni S.S. Korsakova [Zh Nevrol Psikhiatr Im S S Korsakova] 2013; Vol. 113 (2 Pt 2), pp. 6-9. |
| Abstrakt: |
Multiple sclerosis is a classic multifactorial disease in which etiology interaction of external factors and structural features of a large number of genes plays an important role. Identifying risk factors for multiple sclerosis and creating an integrated model of pathogenesis are urgent tasks of neurology. Revealing true risk factors is possible only in studies with sufficient statistical power, so with a large amount of samples. We conducted the association study of CD40 gene's polymorphisms and multiple sclerosis among residents of the Russian Federation. The results demonstrated the need to combine data from different researchers in clinical studies to increase the power of the study. |
| Databáze: |
MEDLINE |
| Externí odkaz: |
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