Combined Pd/C and Montmorillonite Catalysis for One-Pot Synthesis of Benzimidazoles.

Autor: Weires NA; Department of Chemistry, University of Idaho Moscow, ID, 83844-2343, USA., Boster J, Magolan J
Jazyk: angličtina
Zdroj: European journal of organic chemistry [European J Org Chem] 2012 Nov 01; Vol. 2012 (33), pp. 6508-6512. Date of Electronic Publication: 2012 Oct 22.
DOI: 10.1002/ejoc.201201101
Abstrakt: A series of nineteen benzimidazoles are prepared from ortho -nitroanilines via one-pot transfer hydrogenation, condensation, and dehydrogenation enabled by the concurrent use of two heterogeneous catalysts: montmorillonite-K10 and Pd/C. This strategy is further employed to accomplish a five-step, three-component synthesis of an antifungal benzimidazoquinazoline using a simple one-pot procedure.
Databáze: MEDLINE