| Autor: |
James A; Oxford University Hospitals Trust, Oxford, UK., Blagojevic J, Benham SW, Cornall R, Frater J |
| Jazyk: |
angličtina |
| Zdroj: |
BMJ case reports [BMJ Case Rep] 2013 Mar 18; Vol. 2013. Date of Electronic Publication: 2013 Mar 18. |
| DOI: |
10.1136/bcr-2012-008340 |
| Abstrakt: |
We present a case of azathioprine hypersensitivity presenting as septic shock with associated encephalopathy. The patient was presented with rapid onset of fever, hypotension, confusion and a rapidly declining conscious level. He was admitted to the intensive care unit where he received numerous invasive investigations and treatments with broad-spectrum antibiotics, antivirals and antifungals. All microbial cultures were negative. The patient-consistent with azathioprine hypersensitivity-made a spontaneous recovery after 7 days. The case shows that a time line of drug initiation is a key part of the medical history and consideration of azathioprine hypersensitivity could avoid unnecessary interventions and excessive antimicrobial use. |
| Databáze: |
MEDLINE |
| Externí odkaz: |
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