Stimulating whole saliva affects the response of antimicrobial proteins to exercise.

Autor: Allgrove JE; School of Life Sciences, Kingston University, London, UK.; School of Sport, Exercise and Health Sciences, Loughborough University, Loughborough, UK., Oliveira M; School of Sport, Exercise and Health Sciences, Loughborough University, Loughborough, UK., Gleeson M; School of Sport, Exercise and Health Sciences, Loughborough University, Loughborough, UK.
Jazyk: angličtina
Zdroj: Scandinavian journal of medicine & science in sports [Scand J Med Sci Sports] 2014 Aug; Vol. 24 (4), pp. 649-55. Date of Electronic Publication: 2013 Mar 19.
DOI: 10.1111/sms.12056
Abstrakt: This study investigated the salivary secretion rates of antimicrobial proteins in response to prolonged, exhaustive exercise in both stimulated (STIM) and unstimulated (UNSTIM) saliva flow sample methods. Twenty-four trained men cycled for 2.5 h at 60% V̇O₂max and then to exhaustion at 75% V̇O₂max. Timed collections of whole saliva were made before exercise, mid-exercise, at the end of the moderate exercise bout and post-exhaustive exercise. After each UNSTIM collection, a STIM sample was collected following chewing flavored gum for 1 min. Saliva was analysed for lysozyme, α-amylase and salivary immunoglobulin A (s-IgA), and secretion rates were calculated. Saliva flow was 156% higher in STIM compared with UNSTIM (P < 0.001) and decreased with exercise in STIM only (P < 0.001). Exercise increased lysozyme and α-amylase levels and secretion rates were 144% higher and 152% higher in STIM compared with UNSTIM for lysozyme and α-amylase, respectively (all P < 0.001). S-IgA concentration (P < 0.05) and secretion rate (P < 0.001) increased with exercise but were both lower in STIM compared with UNSTIM (P < 0.001). In conclusion, a STIM saliva flow collection during exercise by chewing flavored gum increased the quantity of saliva and the secretion of lysozyme and α-amylase, but had a limited impact on the secretion of s-IgA.
(© 2013 John Wiley & Sons A/S. Published by John Wiley & Sons Ltd.)
Databáze: MEDLINE
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