Autor: |
Hays KE; 1Department of Pharmacy, University of Washington, Seattle, WA, USA., Ryu RJ, Swisher EM, Reed E, McManus T, Rybeck B, Petros WP, Hebert MF |
Jazyk: |
angličtina |
Zdroj: |
Journal of human lactation : official journal of International Lactation Consultant Association [J Hum Lact] 2013 Nov; Vol. 29 (4), pp. 469-72. Date of Electronic Publication: 2013 Mar 14. |
DOI: |
10.1177/0890334413479671 |
Abstrakt: |
Cisplatin, a platinum-based chemotherapy agent, is commonly used in treating cancers that may affect women of childbearing age, including cervical cancer, triple-negative breast cancer, and pediatric tumors in adolescents. The authors found that platinum was undetectable in breast milk at 66 hours and beyond following a 70-mg dose of intravenous cisplatin. Relative infant dose of platinum was calculated to be between 0.29% and 0.40% of the maternal dose corrected for body weight. This case demonstrates minimal exposure to platinum via breast milk, following a single 70-mg intravenous dose of cisplatin. |
Databáze: |
MEDLINE |
Externí odkaz: |
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