Contact sensitization to modern wound dressings in 70 patients with chronic leg ulcers.
| Autor: | Renner R; Klinik für Dermatologie, Venerologie und Allergologie, Universitätsklinikum Leipzig A.ö.R., Leipzig, Germany. regina.renner@uk-erlangen.de, Simon JC, Treudler R |
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| Jazyk: | angličtina |
| Zdroj: | Dermatitis : contact, atopic, occupational, drug [Dermatitis] 2013 Mar-Apr; Vol. 24 (2), pp. 60-3. |
| DOI: | 10.1097/DER.0b013e318284d9f2 |
| Abstrakt: | Background: Patients with chronic leg ulcers typically experience contact allergy to topical treatments. Although declared as hypoallergenic, modern wound dressings have caused several reported cases of contact allergy. Objective: The aim of the study was to evaluate any allergenic potential of modern wound dressings in patients with leg ulcers. Methods: Seventy-one patients were included in our prospective observation. Patch tests were performed with a selection of 10 modern wound dressings and with selected allergens according to series of the German Contact Dermatitis Research Group (DKG). Results: Of 70 patients eligible for evaluation, 12 (17%) were positive for the hydrogel NuGel, followed by the hydrocolloid NuDerm (n = 7/70, 10%) and the ionic silver-containing wound dressing Aquacel Ag and the gauze Adaptic (both n = 4/70, 5%). Patients with recalcitrant ulcers of prolonged duration showed a significant higher number of epicutaneous sensitizations to wound dressings than patients with shorter ulcer duration. Conclusions: The allergenic potential of modern wound dressings should not be underestimated. There is need for precise declaration of all ingredients. |
| Databáze: | MEDLINE |
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