[Effects of plant polysaccharide paliustran on the growth of human tumor transplants in athymic mice].

Autor: Bukharova IK, Osokina LI, Revazova ES, Moroz LV
Jazyk: ruština
Zdroj: Voprosy onkologii [Vopr Onkol] 1990; Vol. 36 (4), pp. 448-51.
Abstrakt: Plant polysaccharide palyustran inhibited the growth of human lung carcinoma P-1 transplanted to athymic mice by 60% but failed to do so in human rhabdomyosarcoma. Treatment with palyustran was followed by a 2-fold decrease in lympho- and granulocyte levels, selective inhibition of succinate dehydrogenase and alpha-glycerophosphate dehydrogenase activity in tumor cells and--in single cases--metastatic involvement of the liver.
Databáze: MEDLINE