Comparison of (18)F-FDG PET/CT and (68)Ga-DOTATATE PET/CT imaging in metastasized Merkel cell carcinoma.

Autor: Epstude M; Departments of Nuclear Medicine and Radiology, Cantonal Hospital Lucerne, Lucerne, Switzerland., Tornquist K, Riklin C, di Lenardo F, Winterhalder R, Hug U, Strobel K
Jazyk: angličtina
Zdroj: Clinical nuclear medicine [Clin Nucl Med] 2013 Apr; Vol. 38 (4), pp. 283-4.
DOI: 10.1097/RLU.0b013e318281658e
Abstrakt: Merkel cell carcinoma (MCC) is a rare but very aggressive neuroendocrine tumor of the skin in elderly patients with higher mortality compared with melanoma. No evidence-based standardized chemotherapy exists for metastasized patients.We report the case of an 87-year-old patient with the history of resection of a large MCC of the parietal scalp planned for radiotherapy and staged with FDG PET/CT showing disseminated distant metastases. Ga-DOTATATE PET/CT revealed more extensive tumor load compared with FDG, and due to the intensive expression of somatostatin receptors the patient qualified for Y DOTATOC therapy.
Databáze: MEDLINE