| Autor: |
Bakker WJ; Department of Pathobiology, Faculty of Veterinary Medicine, Utrecht University, Utrecht, The Netherlands., Weijts BG, Westendorp B, de Bruin A |
| Jazyk: |
angličtina |
| Zdroj: |
Transcription [Transcription] 2013 Mar-Apr; Vol. 4 (2), pp. 62-6. Date of Electronic Publication: 2013 Feb 14. |
| DOI: |
10.4161/trns.23680 |
| Abstrakt: |
Recently, we showed that E2F7 and E2F8 (E2F7/8) are critical regulators of angiogenesis through transcriptional control of VEGFA in cooperation with HIF. (1) Here we investigate the existence of other novel putative angiogenic E2F7/8-HIF targets, and discuss the role of the RB-E2F pathway in regulating angiogenesis during embryonic and tumor development. |
| Databáze: |
MEDLINE |
| Externí odkaz: |
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