| Autor: |
de Groot PW; Regional Center for Biomedical Research, Albacete Science and Technology Park, University of Castilla-La Mancha, Albacete, Spain., Bader O, de Boer AD, Weig M, Chauhan N |
| Jazyk: |
angličtina |
| Zdroj: |
Eukaryotic cell [Eukaryot Cell] 2013 Apr; Vol. 12 (4), pp. 470-81. Date of Electronic Publication: 2013 Feb 08. |
| DOI: |
10.1128/EC.00364-12 |
| Abstrakt: |
Understanding the pathogenesis of an infectious disease is critical for developing new methods to prevent infection and diagnose or cure disease. Adherence of microorganisms to host tissue is a prerequisite for tissue invasion and infection. Fungal cell wall adhesins involved in adherence to host tissue or abiotic medical devices are critical for colonization leading to invasion and damage of host tissue. Here, with a main focus on pathogenic Candida species, we summarize recent progress made in the field of adhesins in human fungal pathogens and underscore the importance of these proteins in establishment of fungal diseases. |
| Databáze: |
MEDLINE |
| Externí odkaz: |
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