| Autor: |
de Souza JE; Ludwig Institute for Cancer Research, São Paulo Branch at Hospital Alemão Oswaldo Cruz, São Paulo, Brazil., Galante PA, de Almeida RV, da Cunha JP, Ohara DT, Ohno-Machado L, Old LJ, de Souza SJ |
| Jazyk: |
angličtina |
| Zdroj: |
Cancer immunity [Cancer Immun] 2012; Vol. 12, pp. 15. Date of Electronic Publication: 2012 Dec 28. |
| Abstrakt: |
Cell surface proteins (CSPs) are excellent targets for the development of diagnostic and therapeutic reagents, and it is estimated that 10-20% of all genes in the human genome encode CSPs. In an effort to integrate all data publicly available for genes encoding cell surface proteins, a database (SurfaceomeDB) was developed. SurfaceomeDB is a gene-centered portal containing different types of information, including annotation for gene expression, protein domains, somatic mutations in cancer, and protein-protein interactions for all human genes encoding CSPs. SurfaceomeDB was implemented as an integrative and relational database in a user-friendly web interface, where users can search for gene name, gene annotation, or keywords. There is also a streamlined graphical representation of all data provided and links to the most important data repositories and databases, such as NCBI, UCSC Genome Browser, and EBI. |
| Databáze: |
MEDLINE |
| Externí odkaz: |
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