Quantification of viral loads lower than 50 copies per milliliter by use of the Cobas AmpliPrep/Cobas TaqMan HIV-1 test, version 2.0, can predict the likelihood of subsequent virological rebound to >50 copies per milliliter.

Autor: Álvarez Estévez M; Microbiology Service, Hospital Universitario San Cecilio, Granada, Spain., Chueca Porcuna N, Guillot Suay V, Peña Monge A, García García F, Muñoz Medina L, Vinuesa García D, Parra Ruiz J, Hernández-Quero J, García García F
Jazyk: angličtina
Zdroj: Journal of clinical microbiology [J Clin Microbiol] 2013 May; Vol. 51 (5), pp. 1555-7. Date of Electronic Publication: 2013 Feb 06.
DOI: 10.1128/JCM.00100-13
Abstrakt: After 1 year of follow-up, patients on HAART with a baseline viral load (VL) of <20 copies/ml showed significantly lower odds of virological rebound to two consecutive VLs of >50 copies/ml than those with baseline VLs of 20 to 39 and 40 to 49 (P < 0.001). The time to virological rebound was also significantly shorter (P < 0.001) for the groups with baseline VLs of 20 to 39 and 40 to 49.
Databáze: MEDLINE