Front-loaded smear microscopy for the diagnosis of pulmonary TB in Tripoli, Libya.
| Autor: | Gammo M; Parasitology Department, Al Zawiya University, Zawiya, Libya., Lamaric W, Hadida M, Abuazza A, Askar NA, Yassin MA, Cuevas LE |
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| Jazyk: | angličtina |
| Zdroj: | Transactions of the Royal Society of Tropical Medicine and Hygiene [Trans R Soc Trop Med Hyg] 2013 Feb; Vol. 107 (2), pp. 137-9. Date of Electronic Publication: 2012 Dec 14. |
| DOI: | 10.1093/trstmh/trs023 |
| Abstrakt: | Background: Diagnosis of pulmonary TB by conventional smear microscopy requires patient attendance on 2 consecutive days. We investigated whether collecting sputum on-the-spot for smear microscopy on the day the patient presented was as sensitive and specific for diagnosis as the conventional spot-morning-spot scheme. Method: We enrolled 412 adults who presented between January 2009 and October 2010 at the National Centre for TB Control in Tripoli, Libya, with cough of >2 weeks' duration, into a cross-sectional survey collecting four sputum specimens: on-the-spot and Xspot on Day 1; morning and on-the-spot on Day 2. Results: 97 (24%) of 401 culture results were culture positive. Spot-Xspot and spot-morning smear microscopy had, respectively, 65% and 66% sensitivity and 97% and 96% specificity (p > 0.5). Spot-Xspot-morning and Spot-morning-spot smear-microscopy had, respectively, 67% and 66% sensitivity and 96% and 96% specificity (p > 0.5). Conclusion: For the diagnosis of pulmonary TB, the sensitivity and specificity of front-loaded (same-day) smear microscopy is similar to that of the standard smear microscopy scheme. |
| Databáze: | MEDLINE |
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