| Autor: |
Fox CL Jr; College of Physicians and Surgeons, Columbia University, New York, New York 10032., Rao TN, Azmeth R, Gandhi SS, Modak S |
| Jazyk: |
angličtina |
| Zdroj: |
The Journal of burn care & rehabilitation [J Burn Care Rehabil] 1990 Mar-Apr; Vol. 11 (2), pp. 112-7. |
| DOI: |
10.1097/00004630-199003000-00004 |
| Abstrakt: |
One percent silver sulfadiazine has been commonly used as a topical antimicrobial agent after a burn injury. Incidence of burn wound colonization by Staphylococcus aureus in patients treated with silver sulfadiazine has spurred research for other agents. A topical preparation that contains zinc and sulfadiazine (Zad-G) was evaluated for in vitro antibacterial spectrum and in vivo efficacy. Muscle biopsy specimens of rats treated with Zad-G appear to have fewer colonies of S. aureus than groups treated with silver sulfadiazine. Topical therapy with Zad-G for patients with burns was comfortable, reduced wound infection, and was comparable to therapy with silver sulfadiazine. A topical Zad-G preparation that contains zinc sulfadiazine appears to be an effective alternative to silver sulfadiazine in the treatment of burn wounds. |
| Databáze: |
MEDLINE |
| Externí odkaz: |
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