Case report: atenolol overdose successfully treated with hemodialysis.

Autor: Huang SH; Department of Medicine, London Health Sciences Centre, Nephrology Division, Western University, London, Canada., Tirona RG, Ross C, Suri RS
Jazyk: angličtina
Zdroj: Hemodialysis international. International Symposium on Home Hemodialysis [Hemodial Int] 2013 Oct; Vol. 17 (4), pp. 652-5. Date of Electronic Publication: 2013 Jan 24.
DOI: 10.1111/hdi.12020
Abstrakt: Owing to the drug's favorable hydrophilic and pharmacokinetic characteristics, a number of case reports have demonstrated effective treatment of atenolol overdose with hemodialysis. However, the efficiency of atenolol clearance throughout hemodialysis treatments has not previously been examined. In this report, a patient with impaired renal function was successfully treated with two 5-hour intermittent high-flux high-efficiency hemodialysis therapies after atenolol overdose. Serial atenolol levels were measured during his hemodialysis treatments. We observed an over 50% plasma atenolol concentration reduction after each 5-hour hemodialysis therapy. Hemodialysis therapy is an effective treatment for atenolol overdose, especially in patients with impaired renal function.
(© 2013 The Authors. Hemodialysis International © 2013 International Society for Hemodialysis.)
Databáze: MEDLINE
Externí odkaz: